Phentermine and Topiramate: Legit Combination for Weight Loss or Scam?

How much weight can you lose on phentermine and topiramate?

Phentermine and Topiramate Reviews, Side Effects, Drug Reactions, and Natural Alternatives

Weight loss acquires so many different things, some of them are related to drug use. Phentermine and topiramate are over the prescription version of weight loss medication that has been used to treat obesity over the years. 

Phentermine and Topiramate combination is becoming not only the option for over-weight people which is why they are moving towards anything comparable to phentermine.

What drug is similar to phentermine, this can be answered when you know enough about phentermine itself. 

About Phentermine and Topiramate

Phentermine and Topiramate are two different drugs that are used in a combination to treat obesity. [1]

When you look at them individually, phentermine is a sympathomimetic amine and Topiramate is the carbonic anhydrase inhibitor that is used to treat epilepsy and migraine pain. 

Once they are combined, the anorectic property of phentermine is exceeded, thus providing lipid-lowering effects and lower blood pressure.

Nowadays, it’s not so a common practice for doctors to prescribe phentermine and topiramate to their patients because of the underlying side effects.

Who Shall Use it?

Phentermine and topiramate extended-release dose is taken by the adults to treat obesity.

The risk of high blood pressure and high blood cholesterol level is way too high in such individuals who are given phentermine and topiramate combination.

The use of phentermine and topiramate is recommended with a reduced-calorie diet and exercise plan.

Phentermine is an anorectic that suppresses the user’s appetite while topiramate is an anti-convulsant, the combination decreased the appetite in a patient for more time than taking phentermine and topiramate separately. [2]

The Proper Dosage

There is a capsule that has extended-release technology that gradually releases the smaller particles of drug particles over an extended period of time.

Users are only to take a capsule without food once a day in the morning.

If taken in the evening, phentermine and topiramate can cause sleep disturbance in users, that’s why intake in the morning is advised.

The physician will guide you with additional tips to understand the main part about how to take phentermine and topiramate. 

Usually, doctors around the US who prescribe phentermine and topiramate to their patients start with a low dose. [3]

Then increase the dose gradually after 14 days, completing 12 weeks’ regimen the doctor will then ask you if you have lost any weight.

Some patients who have lost weight are advised to stop the dosage at the moment.

Phentermine is an addictive drug that in combination with topiramate causes addiction in users. It is never recommended to take large doses of phentermine and topiramate or using the drug for a prolonged period.

Side Effects of Phentermine and Topiramate 

weight loss effects of Phentermine and Topiramate on body

Taking Phentermine and Topiramate is medically beneficial to reduce BMI in obese patients. But it also comes along with many unwanted effects, in case of the continuation of the following side effects it is your duty to seek medical help immediately. 

  • Convulsions/Seizures
  • Chest Discomfort
  • Mood Changes
  • Muscle Cramps
  • Palpitation/Racing Heart
  • Shortness of Breath
  • Nausea
  • Overtiredness

The rare but severe side effects of phentermine and topiramate are blood in urine, sharp back pain, pain in the genitals which must be addressed right away to your healthcare provider. [4]

Beware: Before Taking Phentermine and Topiramate

As a loyal patient, you have to discuss your medical history with your doctor.

If by any chance you have been using Mono-Amino Oxidase Inhibitors in the past 14 days, you must tell the doctor right away because that can induce a dangerous drug reaction.

The MAOs in this list are linezolid, methylene blue injection, selegiline, phenelzine, rasagiline, and others. 

In case of the following medical conditions, it is not advised to take phentermine and topiramate because of the occurrence of allergic reactions. 

  • Hyperthyroidism
  • Glaucoma
  • Pregnancy

Pregnant females should not undergo phentermine and topiramate treatment.

Both phentermine and topiramate are associated with bringing up the teratogenic effects in pregnant women which can even lead to certain birth defects. Even phentermine split dose is not recommended during pregnancy. 


Phentermine and topiramate for weight loss are not approved for those who are under 18, also tell the doctor if you have a history of them. 

  • Heart attack or stroke
  • High blood pressure
  • Diabetes or high sugar levels
  • Kidney disorders i.e stones or dialysis
  • Metabolic acidosis, a condition where too much acid is in your system
  • Liver disease
  • Chronic diarrhea
  • Seizures
  • Depression and excessive mood swings

Topiramate is known to increase the level of acid in the blood and thus supporting metabolic acidosis. This can not only cause kidney stones but the weakening of bones and growth-related problems to the unborn baby. 

Studies on Topiramate alone concludes that in some patients, it causes suicidal behavior and thoughts for which regular doctor visit is mandatory. Never breastfeed while using phentermine and topiramate in combination. 

Phentermine and Topiramate Overdose

topiramate and phentermine for weight loss

Currently, phentermine and topiramate are used in a combination in the US mostly, you should call the Poison Help Line in case of overdosing phentermine and topiramate which can be fatal.

Symptoms of phentermine and topiramate overdose are panic attacks, hallucinations, confusion, tremors, restless which are then followed by vomiting, nausea, stomach cramps, rapid breathing, seizure, and coma. 


Upon taking phentermine and topiramate with birth control pills, it can cause rough vaginal bleeding.

This drug combination should never be combined with pills that prevent pregnancy, the after-effects are drowsiness and diarrhea in females which calls for a doctor’s help. You must always your doctor before using opioid medication, muscle relaxers, and drugs for anxiety or epilepsy. 

Following drugs cause drug-drug interaction if taken alongside Phentermine and Topiramate. 

  • Valproic Acid (for epilepsy)
  • Birth control pills
  • Methazolamide
  • Insulin and oral diabetes medications
  • Diuretics

Other drugs that may affect the absorption and metabolism of phentermine and topiramate are over the counter ones. These are vitamins and herbal products that may cause interactions on a mild scale.

Over The Counter Phentermine and Topiramate Alternative

Topamax and phentermine weight loss success stories are only a few, these are the patients who had no quality of life ensured and those who were on a verge of getting cardiac arrest due to being extremely obese. 

No doubt the drug combination can be pretty fatal when comparing to the diet pills available over the counter

Phen375 - best phentermine and topiramate alternatives over the counter

Not just any diet pills that you see online but the complete phentermine alternatives that are natural and safe.

You can find the best available option for phentermine and topiramate alternatives if you take a look around. Supplements with Garcinia Cambogia, Raspberry Ketone, and herbal extracts are known to be beneficial for reducing weight.

While most men and women are using the over the counter diet pills and sharing their success stories online, this almost made us say bye-bye to Phentermine and Topiramate. 

Related Information

Keep in touch with your doctor and the lab results because they will show the correct response to the drug and dosages provided to you.

Never let others take your medication, by the laws of the US it is illegal to supply even a small quantity of phentermine or topiramate. 

Phentermine and Topiramate are both classified as a controlled substance which is only obtained if you have a prescription.

The pharmacist only refills phentermine a limited number of times.

You should also discuss with your doctor about the intake of multi-vitamin supplements or any minerals before starting phentermine and topiramate dosage.

Phentermine and Topiramate Results

Phentermine and Topiramate over the counter is not a real term, the drugs are only available on prescription which users must have with them all the time.

The combination is known as beneficial for weight loss but again, it comes with a wide array of side effects and drug interactions which is enough for our understandings about its use. [5]

non prescription phentermine weight loss pills

Stay extra precautions while taking phentermine and topiramate for weight loss, fill your doctor with everything he needs to know.

You can also discuss with him about finding the best phentermine alternative which may be natural in terms of effects.

The benefit of the best phentermine natural versions is they don’t come with any side effects as compared to what phentermine and topiramate do to your body. 

Finding the best non -prescription alternative to phentermine is very easy when you look online.

There is no loss for your health to use these natural supplements, only those mimicking the effect of phentermine naturally. You don’t need the topiramate with phentermine anymore to lose weight.

Phentermine and Topiramate dosage is only determined by the doctors, based on your BMI and previous medical history. 


Top 10 Keto Pills Review 2022 Updated: Is Shark Tank Keto Diet Pills Strong Or Scam BHB Keto Weight Loss Pills At Walmart, GNC And Amazon

Fivecbd CBD Gummies Review 2022: Is Fivecbd Gummies Legit CBD + THC Gummies Online Or Fake Full Spectrum CBD Gummies Near Me

Keto Blast Gummies Review 2022 Update: Is It Best Shark Tank Keto Blast Gummy Bears Or SCAM

Joyorganics CBD Gummies For Sale Online In 2023: Buy Joyorganicss CBD Gummies In USA, UK, Australia And Canada

HempBombs CBD Gummies For Sale Online In US, UK, Australia, And Canada: Buy CBD Hempbombs Gummies For Pain, Anxiety And Sleep